TNFSF9 抗体
Quick Overview for TNFSF9 抗体 (ABIN6938631)
抗原
See all TNFSF9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human CD137L protein
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亚型
- IgG2a kappa
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 101-200) antibody
TNFSF9 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 42-253) antibodyTNFSF9 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 105-309) antibodyTNFSF9 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) antibodyTNFSF9 适用: 人 FACS, IHC, StM 宿主: 小鼠 Monoclonal CD137L-1547 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 52-254) antibodyTNFSF9 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM68 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (Extracellular Domain) antibodyTNFSF9 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 41B436 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 52-254) antibodyTNFSF9 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 145-254) antibodyTNFSF9 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 145-254) antibodyTNFSF9 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells in 0.1ml), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Raji, 293T, HEK293 cells. Kidney.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
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别名
- TNFSF9
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背景
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4-1BB ligand, 4-1BBL, CD137L, ILA ligand (TNF related), Ly63l, Tumor necrosis factor ligand 5A (TNLG5A), Tumor necrosis factor ligand superfamily member 9 (TNFSF9),CD137L / 4-1BBL / TNFSF9
Cellular localisation: Cell Surface and Cytoplasmic -
分子量
- 27kDa
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基因ID
- 8744, 1524
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UniProt
- P41273
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途径
- Activated T Cell Proliferation, Cancer Immune Checkpoints
抗原
-
