TNC 抗体
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- 抗原 See all TNC 抗体
- TNC (Tenascin C (TNC))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNC antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- In Western blotting, it reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
- 无交叉反应
- 大鼠
- 交叉反应 （详细）
- Human. Does not react with Rat.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Human breast carcinoma
- 克隆位点
- SPM319
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TNC Primary Antibody
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anti-Tenascin C (TNC) (AA 513-621) antibody
TNC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tenascin C (TNC) antibodyTNC 适用: 人 WB, IP, IHC (p) 宿主: 小鼠 Monoclonal T2H5 unconjugated
anti-Tenascin C (TNC) (AA 49-181) antibodyTNC 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Tenascin C (TNC) (AA 175-342) antibodyTNC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tenascin C (TNC) (AA 1001-1100) antibodyTNC 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tenascin C (TNC) (AA 49-181) antibodyTNC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tenascin C (TNC) (AA 181-290) antibodyTNC 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tenascin C (TNC) (AA 174-621) antibodyTNC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tenascin C (TNC) antibodyTNC 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SPM319 unconjugated
anti-Tenascin C (TNC) antibodyTNC 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TNC-3635 unconjugated Recombinant Antibody
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) ,Optimal dilution for a specific application should be determined.
Positive_Control: Extracellular matrix in tonsil and blood vessels. Stroma of many tumors such as breast, squamous cell and lung carcinomas. Staining of normal fibroblasts serves as internal positive control.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- TNC (Tenascin C (TNC))
- 别名
- TNC (TNC 产品)
- 背景
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Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion (HXB), JI, Myotendinous antigen, Neuronectin, TNC,Tenascin C (Stromal Marker for Epithelial Malignancy)
Cellular localisation: Connective tissue matrix - 分子量
- 210kDa and 300kDa
- 基因ID
- 3371, 143250
- UniProt
- P24821
- 途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
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