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TIMP2 抗体 (AA 48-220)

This anti-TIMP2 antibody is a 小鼠 单克隆 antibody detecting TIMP2 in ELISA, IHC (f) 和 Coat. Suitable for 人.
产品编号 ABIN6938578
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for TIMP2 抗体 (AA 48-220) (ABIN6938578)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TIMP2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)

克隆位点

TIMP2-2044
  • 抗原表位

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    AA 48-220

    特异性

    It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant human TIMP2 protein fragment (aa 48-220) (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa cells. Normal Placenta. Breast, Colon, Endometrial, Prostate or Ovarian Carcinoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP2

    背景

    Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, Tissue Inhibitor of Metalloproteinase 2,TIMP2 (Tissue Inhibitor of Metalloproteinase 2)
    Cellular localisation: Cytoplasm and Cell Surface

    分子量

    21kDa

    基因ID

    7077, 633514

    UniProt

    P16035

    途径

    cAMP Metabolic Process
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