TFF1 抗体
-
- 抗原 See all TFF1 抗体
- TFF1 (Trefoil Factor 1 (TFF1))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This TFF1 antibody is un-conjugated
-
应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- It recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60 % of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human TFF1 protein
- 克隆位点
- TFF1-2133
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product TFF1 Primary Antibody
-
anti-Trefoil Factor 1 (TFF1) antibody
TFF1 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal TFF1-2133 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 25-84), (pSer2) antibodyTFF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) antibodyTFF1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-87) antibodyTFF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-81) antibodyTFF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-84) antibodyTFF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 57-84) antibodyTFF1 适用: 人, Cynomolgus IHC, StM 宿主: 小鼠 Monoclonal GE2-same as R47-94 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-84) antibodyTFF1 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-88) antibodyTFF1 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-482M unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 25-84) antibodyTFF1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 cells, Breast or Ovarian carcinoma.
- 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
-
- 抗原
- TFF1 (Trefoil Factor 1 (TFF1))
- 别名
- TFF1 (TFF1 产品)
- 背景
-
BCEI, Breast Cancer Estrogen Inducible Protein, Gastrointestinal Trefoil Protein, Gastrointestinal trefoil protein pS2, HP1A, HPS2, pNR2, TFF1, Trefoil Factor 1,pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein)
Cellular localisation: Cytoplasmic - 分子量
- 6.5kDa
- 基因ID
- 7031, 162807
- UniProt
- P04155
- 途径
- EGFR Signaling Pathway
-
