SUMO2 抗体
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- 抗原 See all SUMO2 抗体
- SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SUMO2 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer's disease.
- 交叉反应 （详细）
- Human. Rat. Predicted to show a broad species reactivity.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human SUMO2 protein
- 克隆位点
- SUMO2-1199
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SUMO2 Primary Antibody
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anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibody
SUMO2 适用: 人, 大鼠 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SUMO2-1199 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 63-93) antibodySUMO2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-95) antibodySUMO2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibodySUMO2 适用: 人 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SM23-496 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-95) antibodySUMO2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibodySUMO2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibodySUMO2 适用: 人, 大鼠 IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal SUMO2-1199 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-95) antibodySUMO2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 49-81) antibodySUMO2 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 63-93), (C-Term) antibodySUMO2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2761 unconjugated
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells. Breast carcinoma.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
- 别名
- SUMO2 (SUMO2 产品)
- 别名
- HSMT3 antibody, SMT3B antibody, SMT3H2 antibody, SUMO3 antibody, Smt3A antibody, SMT3A antibody, SMT3H1 antibody, SUMO-3 antibody, Smt3B antibody, Smt3h2 antibody, sumo2 antibody, zgc:92241 antibody, SUMO2 antibody, SUMO-2 antibody, Smt3b antibody, hsmt3 antibody, smt3b antibody, smt3h2 antibody, sumo-2 antibody, PSMT3 antibody, ATSUMO2 antibody, MCO15.11 antibody, MCO15_11 antibody, SMALL UBIQUITIN-LIKE MODIFIER 2 antibody, SUM2 antibody, SUMO 2 antibody, small ubiquitin-like modifier 2 antibody, small ubiquitin-like modifier 2 antibody, small ubiquitin-like modifier 3 antibody, small ubiquitin-like modifier 2b antibody, small ubiquitin-related modifier 2 antibody, small ubiquitin-like modifier 2 S homeolog antibody, small ubiquitin-like modifier 2 L homeolog antibody, SUMO2 antibody, SUMO3 antibody, Sumo2 antibody, sumo2b antibody, LOC714892 antibody, sumo2.S antibody, sumo2.L antibody
- 背景
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HSMT3, Sentrin 2, Small ubiquitin like modifier 2, Small ubiquitin like modifier protein 3, SMT3A, SMT3B, SMT3 homolog 1 (SMT3H1), SMT3 homolog 2 (SMT3H2), SMT3 homolog, SMT3 suppressor of mif two 3 homolog 1, SMT3 suppressor of mif two 3 homolog 2, SMT3 suppressor of mif two 3 homolog 3, Suppressor of mif two 3 homolog 2, Suppressor of mif two 3 homolog 3, Ubiquitin like protein SMT3A, Ubiquitin like protein SMT3B,SUMO-2
Cellular localisation: Nuclear - 分子量
- 11-13kDa
- 基因ID
- 6613, 474005
- UniProt
- P55854
- 途径
- Methionine Biosynthetic Process
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