SERBP1 抗体 (AA 3-139)
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- 抗原 See all SERBP1 抗体
- SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))
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抗原表位
- AA 3-139
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SERBP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-i± and may be involved in chromatin remodeling. It also interacts with PGRMC1 and participates in the transduction of Progesterone s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.
- 交叉反应 （详细）
- Human. Others not tested.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment of human SERBP1 protein (around aa3-139) (exact sequence is proprietary)
- 克隆位点
- SERBP1-3496
- 亚型
- IgG2c kappa
- Top Product
- Discover our top product SERBP1 Primary Antibody
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anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-402) antibody
SERBP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D2-2E9 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-262) antibodySERBP1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-262) antibodySERBP1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5G2 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 3-139) antibodySERBP1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SERBP1-3493 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 3-139) antibodySERBP1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SERBP1-3491 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 3-139) antibodySERBP1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SERBP1-3496 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-262) antibodySERBP1 适用: 人, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4F8 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-402) antibodySERBP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G5-2D7 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-408) antibodySERBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) antibodySERBP1 适用: 人 IHC, ELISA, IHC (p), FACS 宿主: 小鼠 Monoclonal 1D5 unconjugated
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- 应用备注
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Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: K562 or PC3 cells. Human kidney or bladder tissue (IHC).
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))
- 别名
- SERBP1 (SERBP1 产品)
- 别名
- CHD3IP antibody, HABP4L antibody, PAI-RBP1 antibody, PAIRBP1 antibody, 1200009K13Rik antibody, 9330147J08Rik antibody, AL022786 antibody, Pairbp1 antibody, Pai-Rbp1 antibody, Rda288 antibody, cgi-55 antibody, chd3ip antibody, habp4l antibody, pai-rbp1 antibody, pairbp1 antibody, rda288 antibody, hm:zeh0245 antibody, serbp1 antibody, wu:fa12d05 antibody, wu:fb36e07 antibody, wu:fc16f12 antibody, wu:fj13e12 antibody, zgc:55489 antibody, SERPINE1 mRNA binding protein 1 antibody, serpine1 mRNA binding protein 1 antibody, Serpine1 mRNA binding protein 1 antibody, SERPINE1 mRNA binding protein 1 L homeolog antibody, SERPINE1 mRNA binding protein 1a antibody, SERBP1 antibody, Serbp1 antibody, serbp1.L antibody, serbp1a antibody
- 背景
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CGI 55, CHD3IP, Chromodomain helicase DNA binding protein 3 interacting protein, HABP4L, PAI1 RNA-binding protein 1, PAIRBP1, Plasminogen activator inhibitor 1 RNA binding protein, SERPINE1 mRNA binding protein 1,SERBP1 / PAI-RBP1
Cellular localisation: Cytoplasm and nucleus. Also found in perinuclear regions. - 分子量
- 60kDa
- 基因ID
- 26135, 530412
- UniProt
- Q8NC51
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