SERBP1 抗体 (AA 3-139)
Quick Overview for SERBP1 抗体 (AA 3-139) (ABIN6938369)
抗原
See all SERBP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 3-139
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特异性
- SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-i± and may be involved in chromatin remodeling. It also interacts with PGRMC1 and participates in the transduction of Progesterone’s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human SERBP1 protein (around aa3-139) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-402) antibody
SERBP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D2-2E9 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-262) antibodySERBP1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5G2 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-262) antibodySERBP1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 3-139) antibodySERBP1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SERBP1-3491 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 3-139) antibodySERBP1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SERBP1-3493 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 3-139) antibodySERBP1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SERBP1-3496 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-262) antibodySERBP1 适用: 人, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4F8 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-402) antibodySERBP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G5-2D7 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-408) antibodySERBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 311-360) antibodySERBP1 适用: 人, 小鼠, 大鼠, 犬, 猴, Cow, 豚鼠, 马, 兔, Pig, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: K562 or PC3 cells. Human kidney or bladder tissue (IHC).
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))
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别名
- SERBP1
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背景
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CGI 55, CHD3IP, Chromodomain helicase DNA binding protein 3 interacting protein, HABP4L, PAI1 RNA-binding protein 1, PAIRBP1, Plasminogen activator inhibitor 1 RNA binding protein, SERPINE1 mRNA binding protein 1,SERBP1 / PAI-RBP1
Cellular localisation: Cytoplasm and nucleus. Also found in perinuclear regions. -
分子量
- 60kDa
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基因ID
- 26135, 530412
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UniProt
- Q8NC51
抗原
-
