RNLS 抗体 (AA 34-235)
Quick Overview for RNLS 抗体 (AA 34-235) (ABIN6938322)
抗原
See all RNLS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 34-235
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特异性
- Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human RNLS protein fragment (around aa 34-235) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 160-319) antibody
RNLS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 18-342) antibodyRNLS 适用: 人 WB 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 68-242) antibodyRNLS 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1C11E8 unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 201-300) antibodyRNLS 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 18-342) antibodyRNLS 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (Internal Region) antibodyVerified RNLS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (C-Term) antibodyRNLS 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (Middle Region) antibodyRNLS 适用: 人, 小鼠, 大鼠, 马, Pig, 兔, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) antibodyRNLS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 1-342) antibodyRNLS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: 293T cells. Heart or Kidney.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
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别名
- RNLS
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背景
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Chromosome 10 open reading frame 59, MAO C, MAO-C, Monoamine oxidase-C, Renalase, Renalase FAD dependent amine oxidase, RNLS,Renalase (Renal Cell Marker)
Cellular localisation: Secreted -
分子量
- 38kDa
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基因ID
- 55328, 149849
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UniProt
- Q5VYX0
抗原
-
