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Prolactin Receptor 抗体

This 小鼠 单克隆 anti-Prolactin Receptor antibody (Clone B6-2) specifically detects Prolactin Receptor in IF, FACS 和 IHC (f). The antibody is reactive with 人 samples.
产品编号 ABIN6938242
发货至: 中国
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北京 101111
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Quick Overview for Prolactin Receptor 抗体 (ABIN6938242)

抗原

See all Prolactin Receptor (PRLR) 抗体
Prolactin Receptor (PRLR)

适用

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小鼠

克隆类型

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单克隆

标记

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This Prolactin Receptor antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

B6-2
  • 特异性

    It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Semi-Purified human prolactin receptor

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Testicular Carcinoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Prolactin Receptor (PRLR)

    别名

    PRLR

    背景

    CPRLP, hPRL receptor, hPRLrI, Lactogen receptor, OPR, Pr-1, Pr-3, PRL-R, Prolactin receptor delta 7/11, RATPRLR, Secreted prolactin binding protein, Truncated testis-specific box 1-C prolactin receptor,Prolactin Receptor (hPRL Receptor)
    Cellular localisation: Cell surface and cytoplasmic

    分子量

    70kDa

    基因ID

    5618, 368587

    UniProt

    P16471

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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