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PDLIM1 抗体

PDLIM1 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal CPTC-PDLIM1-1 unconjugated
产品编号 ABIN6938142
发货至: 中国
  • 抗原 See all PDLIM1 抗体
    PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))
    适用
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    宿主
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    小鼠
    克隆类型
    • 62
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    单克隆
    标记
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    This PDLIM1 antibody is un-conjugated
    应用范围
    • 57
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    Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    CLP36, also known as PDLIM1, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (-actinin-1, thereby facilitating the association of Clik1 with actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88 % sequence similarity with its rat counterpart, suggesting a conserved function between species.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant human full-length PDLIM1 protein
    克隆位点
    CPTC-PDLIM1-1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PDLIM1 Primary Antibody
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HepG2 cells and extracts from Jurkat. Human heart, colon or spleen.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))
    别名
    PDLIM1 (PDLIM1 产品)
    别名
    CLIM1 antibody, CLP-36 antibody, CLP36 antibody, hCLIM1 antibody, pdlim1 antibody, MGC76041 antibody, MGC64465 antibody, clim1 antibody, wu:fa19a03 antibody, wu:fy34f10 antibody, zgc:110681 antibody, Clim1 antibody, mClim1 antibody, PDLIM1 antibody, PDZ and LIM domain 1 antibody, PDZ and LIM domain 1 L homeolog antibody, PDZ and LIM domain 1 (elfin) antibody, PDLIM1 antibody, Pdlim1 antibody, pdlim1 antibody, pdlim1.L antibody
    背景
    C terminal LIM domain protein 1, carboxy terminal LIM domain protein 1, CLIM1, CLP36, Elfin, Enigma antibody, Enigma homolog antibody, hCLIM1, PDLIM1, PDZ and LIM domain 1,PDZ and LIM Domain 1
    Cellular localisation: Cytoplasm.
    分子量
    36kDa
    基因ID
    9124, 368525
    UniProt
    O00151
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