PDLIM1 抗体
Quick Overview for PDLIM1 抗体 (ABIN6938142)
抗原
See all PDLIM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- CLP36, also known as PDLIM1, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (-actinin-1, thereby facilitating the association of Clik1 with actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88 % sequence similarity with its rat counterpart, suggesting a conserved function between species.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length PDLIM1 protein
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亚型
- IgG1 kappa
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anti-PDZ and LIM Domain 1 (PDLIM1) (AA 1-329) antibody
PDLIM1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-PDZ and LIM Domain 1 (PDLIM1) (AA 2-329) antibodyPDLIM1 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-PDZ and LIM Domain 1 (PDLIM1) (AA 1-329) antibodyPDLIM1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-PDZ and LIM Domain 1 (PDLIM1) (Internal Region) antibodyPDLIM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PDZ and LIM Domain 1 (PDLIM1) (AA 123-232) antibodyPDLIM1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-PDZ and LIM Domain 1 (PDLIM1) antibodyPDLIM1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-PDZ and LIM Domain 1 (PDLIM1) (Center) antibodyPDLIM1 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬 WB, IHC, IP, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-PDZ and LIM Domain 1 (PDLIM1) (Internal Region) antibodyPDLIM1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-PDZ and LIM Domain 1 (PDLIM1) antibodyPDLIM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PDZ and LIM Domain 1 (PDLIM1) (AA 123-232) antibodyPDLIM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HepG2 cells and extracts from Jurkat. Human heart, colon or spleen.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))
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别名
- PDLIM1
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背景
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C terminal LIM domain protein 1, carboxy terminal LIM domain protein 1, CLIM1, CLP36, Elfin, Enigma antibody, Enigma homolog antibody, hCLIM1, PDLIM1, PDZ and LIM domain 1,PDZ and LIM Domain 1
Cellular localisation: Cytoplasm. -
分子量
- 36kDa
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基因ID
- 9124, 368525
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UniProt
- O00151
抗原
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