PAX2A 抗体 (AA 223-354)
Quick Overview for PAX2A 抗体 (AA 223-354) (ABIN6938116)
抗原
See all PAX2A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 223-354
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特异性
- Recognizes a protein of 42kDa, which is identified as PAX2. It is a member of the paired box family of transcription factors, which is required for development and proliferation of the kidney, brain, and mullerian organs. PAX2 genes contain a highly conserved DNA sequence within the paired box region, which encodes a DNA-binding domain, enabling PAX proteins to bind the promoters of specific genes to transcriptionally regulate their expression. PAX2 is specifically expressed in the developing central nervous system, eye, ear, and urogenital tract, and is essential for the development of these organs. In normal adult tissues PAX2 was mainly detected in the urogenital system, including kidney, ureteric epithelium, fallopian tube epithelium, ovary and uterus. In tumors, PAX2 has been detected in renal cell carcinomas, Wilms' tumors, nephrogenic adenomas and papillary serous carcinoma of the ovary. PAX2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa 223-354) human PAX2 protein (exact sequence is proprietary)
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亚型
- IgG2b kappa
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anti-Paired Box Gene 2a (PAX2A) (AA 194-303) antibody
PAX2A 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Paired Box Gene 2a (PAX2A) (AA 223-354) antibodyPAX2A 适用: 人 ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal PAX2-1104 unconjugated
anti-Paired Box Gene 2a (PAX2A) antibodyPAX2A 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Paired Box Gene 2a (PAX2A) (AA 194-304) antibodyPAX2A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2C8C6 unconjugated
anti-Paired Box Gene 2a (PAX2A) (AA 248-282), (C-Term) antibodyPAX2A 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box Gene 2a (PAX2A) antibodyPAX2A 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 小鸡 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Paired Box Gene 2a (PAX2A) (AA 194-304) antibodyPAX2A 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Paired Box Gene 2a (PAX2A) (Middle Region) antibodyPAX2A 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 兔, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box Gene 2a (PAX2A) (AA 1-431) antibodyPAX2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Paired Box Gene 2a (PAX2A) (pSer393) antibodyPAX2A 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: NAMALWA cells. Fetal kidney or Renal Cell Carcinoma (RCC) or Ovarian Carcinoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- PAX2A (Paired Box Gene 2a (PAX2A))
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别名
- PAX2
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背景
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Paired box gene 2, paired box homeotic gene 2, paired box protein 2, Paired box protein Pax-2, Paired box protein Pax2,PAX2 (Renal Cell & Ovarian Carcinoma Marker)
Cellular localisation: Nuclear -
分子量
- 42kDa
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基因ID
- 5076, 155644
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UniProt
- Q02962
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途径
- Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation
抗原
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