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PAX2A 抗体 (C-Term)

PAX2A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043591
发货至: 中国
  • 抗原 See all PAX2A 抗体
    PAX2A (Paired Box Gene 2a (PAX2A))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 248-282, C-Term
    适用
    • 75
    • 35
    • 24
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    人, 小鼠, 大鼠
    宿主
    • 73
    • 7
    克隆类型
    • 66
    • 14
    多克隆
    标记
    • 38
    • 8
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This PAX2A antibody is un-conjugated
    应用范围
    • 54
    • 45
    • 15
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Paired box protein Pax-2(PAX2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    RKHLRADTFT QQQLEALDRV FERPSYPDVF QASEH
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Paired box protein Pax-2(PAX2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: paired box 2
    Protein Name: Paired box protein Pax-2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Pax2 (248-282aa RKHLRADTFTQQQLEALDRVFERPSYPDVFQASEH), identical to the related mouse sequence.
    亚型
    IgG
    Top Product
    Discover our top product PAX2A Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Yang, He, Peng, Zhong, Deng, Yu, Guan, Zuo, Xu: "Matrine suppresses the migration and invasion of NSCLC cells by inhibiting PAX2-induced epithelial-mesenchymal transition." in: OncoTargets and therapy, Vol. 10, pp. 5209-5217, (2017) (PubMed).

  • 抗原
    PAX2A (Paired Box Gene 2a (PAX2A))
    别名
    PAX2 (PAX2A 产品)
    别名
    PAPRS antibody, Opdc antibody, Pax-2 antibody, Pax-2a antibody, XPax-2 antibody, XPax2 antibody, pax-2 antibody, pax2 antibody, xPax-2a antibody, PAXZF-B antibody, cb378 antibody, noi antibody, pax-b antibody, pax2.1 antibody, pax2a1 antibody, pax[zf-b] antibody, paxb antibody, pax2.2 antibody, paired box 2 antibody, paired box 2 L homeolog antibody, paired box 2a antibody, paired box 2b antibody, PAX2 antibody, Pax2 antibody, pax2.L antibody, pax2a antibody, pax2b antibody
    背景
    Paired box gene 2, also known as PAX2, is a protein which in humans is encoded by the PAX2 gene. This gene is mapped to 10q24. PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

    Synonyms: Paired box 2 antibody|Paired box gene 2 antibody|paired box homeotic gene 2 antibody|paired box protein 2 antibody|Paired box protein Pax 2 antibody|Paired box protein Pax-2 antibody|Paired box protein Pax2 antibody|Pax 2 antibody
    基因ID
    5076
    UniProt
    Q02962
    途径
    Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation
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