电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Nkx2-2 抗体 (AA 1-119)

Nkx2-2 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal NX2-1523 unconjugated
产品编号 ABIN6938062
发货至: 中国
  • 抗原 See all Nkx2-2 抗体
    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
    抗原表位
    • 15
    • 9
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-119
    适用
    • 101
    • 50
    • 43
    • 22
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    宿主
    • 66
    • 45
    小鼠
    克隆类型
    • 58
    • 53
    单克隆
    标记
    • 49
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Nkx2-2 antibody is un-conjugated
    应用范围
    • 47
    • 45
    • 39
    • 36
    • 30
    • 12
    • 9
    • 8
    • 7
    • 3
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment (around aa1-119) of human NKX2.2 protein (exact sequence is proprietary)
    克隆位点
    NX2-1523
    亚型
    IgG1 kappa
    Top Product
    Discover our top product Nkx2-2 Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.

    Positive_Control: Pancreas or Ewing's Sarcoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
    别名
    NKX2-2 (Nkx2-2 产品)
    别名
    XeNK-2 antibody, Xnkx2.2 antibody, nkx2-2-A antibody, nkx2.2 antibody, NKX-2.2 antibody, NKX2.2 antibody, NKX2B antibody, Nkx-2.2 antibody, Nkx2.2 antibody, tinman antibody, id:ibd5090 antibody, nk2.2 antibody, nkx2-2 antibody, wu:fc83b01 antibody, zgc:136536 antibody, NK2 homeobox 2 S homeolog antibody, NK2 homeobox 2 antibody, NK2 homeobox 2a antibody, nkx2-2.S antibody, NKX2-2 antibody, Nkx2-2 antibody, nkx2.2a antibody
    背景
    Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman,NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker)
    Cellular localisation: Nuclear
    分子量
    40-50kDa
    基因ID
    4821, 516922
    UniProt
    O95096
    途径
    Dopaminergic Neurogenesis
You are here:
客服