Recombinant NKX2-1 抗体
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- 抗原 See all NKX2-1 抗体
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This NKX2-1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
- 交叉反应 （详细）
- Human. Mouse. Rat.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human full-length TTF-1 protein
- 克隆位点
- NX2-1-1855R
- 亚型
- IgG
- Top Product
- Discover our top product NKX2-1 Primary Antibody
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anti-NK2 Homeobox 1 (NKX2-1) antibody
NKX2-1 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人 WB, FACS, ELISA, IHC 宿主: 兔 Monoclonal 6C11 unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 兔 Monoclonal NX2-1-1855R unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal rNX2-1-690 unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人, 小鼠, 大鼠 FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal 8G7G3-1 unconjugated
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-312R unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) (AA 1-30), (N-Term) antibodyNKX2-1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB28559 unconjugated
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 1 (NKX2-1) (AA 77-158) antibodyNKX2-1 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 2B9 unconjugated
anti-NK2 Homeobox 1 (NKX2-1) (AA 2-1) antibodyNKX2-1 适用: 人 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MAD109, MLE-15, H441-4 or H345 cells. Normal thyroid or lung.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
- 别名
- NKX2-1 (NKX2-1 产品)
- 别名
- BCH antibody, BHC antibody, NK-2 antibody, NKX2.1 antibody, NKX2A antibody, TEBP antibody, TITF1 antibody, TTF-1 antibody, TTF1 antibody, titf1-A antibody, Xnkx-2.1 antibody, NKX2-1 antibody, LOC100227803 antibody, AV026640 antibody, Nkx2.1 antibody, T/EBP antibody, Titf1 antibody, Ttf-1 antibody, nk2.1a antibody, nkx2.1 antibody, nkx2.4a antibody, titf1 antibody, titf1a antibody, NK2 homeobox 1 antibody, NK2 homeobox 1 L homeolog antibody, NK2 homeobox 4b antibody, NKX2-1 antibody, nkx2-1.L antibody, Nkx2-1 antibody, nkx2.4b antibody
- 背景
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BCH, Benign chorea, BHC, Homeobox protein Nkx2.1, NK2 homeobox 1, NKX2.1, NKX2A, TEBP, Thyroid nuclear factor-1, Thyroid specific enhancer binding protein, Thyroid transcription factor-1 (TTF-1), Tin man, TITF1, TTF-1,TTF-1 / NKX2.1 (Thyroid & Lung Epithelial Marker)
Cellular localisation: Nuclear - 分子量
- 40kDa
- 基因ID
- 7080, 94367
- UniProt
- P43699
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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