Recombinant NGFR 抗体 (AA 281-421)
Quick Overview for Recombinant NGFR 抗体 (AA 281-421) (ABIN6938053)
抗原
See all NGFR 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 281-421
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特异性
- It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human p75 NGFR protein fragment (around aa 281-421) (exact sequence is proprietary)
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亚型
- IgG
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anti-Nerve Growth Factor Receptor (NGFR) (AA 301-400) antibody
NGFR 适用: 人, 大鼠, 小鼠 WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 大鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR 适用: 人 IHC, Diff, StM 宿主: 小鼠 Monoclonal NGFR-1964 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 188-203), (Extracellular) antibodyKO Validated NGFR 适用: 人 WB, FACS, IHC, IF, IP, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, Non-Human Primate IHC, Diff, StM 宿主: 兔 Monoclonal NGFR-1997R unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR 适用: 人 IHC, Diff, StM 宿主: 小鼠 Monoclonal rNGFR-1965 unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, Non-Human Primate, 兔, Cat, 雪貂 WB, FACS, IHC (p), IP, ICC, ICFC, MS 宿主: 小鼠 Monoclonal NGFR5 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 2F1C2 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 8G3G10 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 8G3G10 unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Neuronal axons, Schwann cells and perineural cells of peripheral nerves or tumors of nerve sheath differentiation e. G. Schwannoma, Neurofibroma. Soma and axons of sensory neurons and ganglionic satellite cells. Melanomas.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- NGFR (Nerve Growth Factor Receptor (NGFR))
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别名
- NGFR
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背景
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CD271, Gp80-LNGFR, Low affinity nerve growth factor receptor, Low affinity neurotrophin receptor p75NTR, Nerve growth factor receptor (NGFR), p75 ICD, p75 Neurotrophin receptor, Tumor necrosis factor receptor superfamily member 16 (TNFRSF16),NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker)
Cellular localisation: Cell surface and cytoplasmic -
分子量
- 75kDa
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基因ID
- 4804, 415768, 681726
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UniProt
- P08138
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途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
抗原
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