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NAPSA 抗体 (AA 189-299)

This 小鼠 单克隆 antibody specifically detects NAPSA in IHC (f). It exhibits reactivity toward 人.
产品编号 ABIN6938009
发货至: 中国
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Quick Overview for NAPSA 抗体 (AA 189-299) (ABIN6938009)

抗原

See all NAPSA 抗体
NAPSA (Napsin A Aspartic Peptidase (NAPSA))

适用

  • 132
  • 17
  • 9
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 69
  • 64
小鼠

克隆类型

  • 88
  • 45
单克隆

标记

  • 55
  • 12
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 1
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This NAPSA antibody is un-conjugated

应用范围

  • 85
  • 70
  • 45
  • 28
  • 17
  • 17
  • 14
  • 12
  • 9
  • 5
  • 1
  • 1
  • 1
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

NAPSA-3309
  • 抗原表位

    • 57
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    AA 189-299

    特异性

    Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant human Napsin A protein fragment (aa189-299) (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Lung adenocarcinoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    NAPSA (Napsin A Aspartic Peptidase (NAPSA))

    别名

    NAPSA

    背景

    ASP4, Aspartyl protease 4, KAP, Kidney derived aspartic protease like protein (Kdap), NAP1, NAPA, Napsa, napsin A aspartic peptidase, Pronapsin A, SNAPA,Napsin A (Lung Adenocarcinoma Marker)
    Cellular localisation: Cytoplasmic

    分子量

    37kDa

    基因ID

    9476, 512843

    UniProt

    O96009

    途径

    Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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