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MMP2 抗体 (AA 444-575)

MMP2 适用: 人 WB 宿主: 小鼠 Monoclonal MMP2-1501 unconjugated
产品编号 ABIN6937878
发货至: 中国
  • 抗原 See all MMP2 抗体
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    抗原表位
    • 16
    • 16
    • 16
    • 9
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 444-575
    适用
    • 143
    • 79
    • 63
    • 49
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    宿主
    • 120
    • 39
    小鼠
    克隆类型
    • 119
    • 40
    单克隆
    标记
    • 72
    • 14
    • 13
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMP2 antibody is un-conjugated
    应用范围
    • 127
    • 56
    • 51
    • 39
    • 39
    • 34
    • 29
    • 25
    • 18
    • 14
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    特异性
    It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant human MMP2 protein fragment (aa 444-575) (exact sequence is proprietary)
    克隆位点
    MMP2-1501
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MMP2 Primary Antibody
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL) Optimal dilution for a specific application should be determined.

    Positive_Control: U-138 MG or U-87 MG cells. Placenta or Colon Carcinoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    别名
    MMP2 (MMP2 产品)
    别名
    2-MMP antibody, CG1794 antibody, DM2-MMP antibody, Dm2-MMP antibody, Dmel\\CG1794 antibody, MMP2 antibody, anon-WO0118547.84 antibody, dm-2MMP antibody, dmmp2 antibody, l(2)02353 antibody, mmp2 antibody, wu:fa99h12 antibody, wu:fk89d01 antibody, fgmmp-2 antibody, Mmp-2 antibody, LOC100135793 antibody, Clg4a antibody, GelA antibody, MMP-2 antibody, CLG4 antibody, CLG4A antibody, MMP-II antibody, MONA antibody, TBE-1 antibody, matrix metallopeptidase 2 antibody, Matrix metalloproteinase 2 antibody, matrix metalloproteinase 2 antibody, matrix metalloproteinase-2 antibody, MMP2 antibody, Mmp2 antibody, mmp2 antibody, LOC657982 antibody, LOC100135793 antibody
    背景
    72kD type IV collagenase, CLG4A, Collagenase Type 4 alpha, Collagenase type IV A, Gelatinase A, Gelatinase alpha, Gelatinase neutrophil, Matrix metalloproteinase-2, MMP2, MONA, Neutrophil gelatinase, PEX, TBE-1,MMP2 / Collagenase Type IV A (Tumor Metastasis Marker)
    Cellular localisation: Cytoplasmic and Cell Surface
    分子量
    72kDa (Pro), 63kDa (cleaved)
    基因ID
    4313, 513617
    UniProt
    P08253
    途径
    Activation of Innate immune Response
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