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MME 抗体

MME 适用: 人 FACS, WB, IHC, IF 宿主: 小鼠 Monoclonal MME-1620 unconjugated
产品编号 ABIN6937870
发货至: 中国
  • 抗原 See all MME 抗体
    MME (Membrane Metallo-Endopeptidase (MME))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MME antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    特异性
    Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human CD10 protein (MME)
    克隆位点
    MME-1620
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MME Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: Ramos cells (FACS/IF). Jurkat or LnCap lysates (WB). Kidney (IHC).

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    MME (Membrane Metallo-Endopeptidase (MME))
    别名
    MME (MME 产品)
    别名
    CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody
    物质类
    Chemical
    背景
    Atriopeptidase, Common acute lymphocytic leukemia antigen (CALLA), Enkephalinase (EPN), gp100, Membrane metalloendopeptidase (MME), Neprilysin, Neutral endopeptidase (NEP), Skin fibroblast elastase (SFE),CD10 (Membrane Metalloendopeptidase)
    Cellular localisation: Cell Surface and Cytoplasmic
    分子量
    100kDa
    基因ID
    4311, 307734
    UniProt
    P08473
    途径
    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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