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MLANA 抗体

MLANA 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal MLANA-1761R unconjugated
产品编号 ABIN6937854
发货至: 中国
  • 抗原 See all MLANA 抗体
    MLANA (Melan A (MLANA))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MLANA antibody is un-conjugated
    应用范围
    • 127
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
    无交叉反应
    小鼠, 大鼠
    交叉反应 (详细)
    Human. Horse. Does not react with Mouse or Rat.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant hMART-1 protein
    克隆位点
    MLANA-1761R
    亚型
    IgG2b kappa
    Top Product
    Discover our top product MLANA Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: SK-MEL-13 and SK-MEL-19 melanoma cell lines. Human melanoma tissues.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    MLANA (Melan A (MLANA))
    别名
    MLANA (MLANA 产品)
    别名
    A930034P04Rik antibody, Mart1 antibody, MART-1 antibody, MART1 antibody, melan-A antibody, Mlana antibody, MLANA antibody
    背景
    Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA,MART-1 / Melan-A / MLANA (Melanoma Marker)
    Cellular localisation: Cytoplasmic
    分子量
    20-22kDa (doublet)
    基因ID
    2315, 154069
    UniProt
    Q16655
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