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LHCGR 抗体 (AA 70-410)

LHCGR 适用: 人 IF, FACS 宿主: 小鼠 Monoclonal LHCGR-1415 unconjugated
产品编号 ABIN6937783
发货至: 中国
  • 抗原 See all LHCGR 抗体
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    抗原表位
    • 20
    • 15
    • 6
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-410
    适用
    • 64
    • 32
    • 24
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 24
    • 1
    小鼠
    克隆类型
    • 45
    • 24
    单克隆
    标记
    • 28
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LHCGR antibody is un-conjugated
    应用范围
    • 48
    • 29
    • 25
    • 20
    • 14
    • 13
    • 13
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS)
    特异性
    Recognizes a protein of 78-85 kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment (around aa 70-410) of human LHCGR protein (exact sequence is proprietary)
    克隆位点
    LHCGR-1415
    亚型
    IgG1 kappa
    Top Product
    Discover our top product LHCGR Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: HepG2 or Jurkat cells. Ovary or Testis.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    别名
    LHCGR (LHCGR 产品)
    别名
    HHG antibody, LCGR antibody, LGR2 antibody, LH/CG-R antibody, LH/CGR antibody, LHR antibody, LHRHR antibody, LSH-R antibody, ULG5 antibody, Gpcr19-rs1 antibody, LH-R antibody, Lhr antibody, LSHR antibody, lhr antibody, GTHR-II antibody, zfGTHR-II antibody, LHCGR antibody, LOC100222883 antibody, lh-r antibody, LOC100305044 antibody, luteinizing hormone/choriogonadotropin receptor antibody, luteinizing hormone/choriogonadotropin receptor L homeolog antibody, luteinizing hormone receptor antibody, LHCGR antibody, Lhcgr antibody, lhcgr antibody, lhcgr.L antibody, lhr antibody, LOC100305044 antibody
    背景
    Gonadotropin receptor, GTHR-II, HHG, LCGR, LGR2, LH-R, LH/CG-R, LH/CGR, LHCGR, LHR, LHRHR, LSH-R, Luteinizing hormone receptor, Luteinizing hormone/choriogonadotropin receptor, Lutropin choriogonadotropic receptor, Lutropin-choriogonadotropic hormone receptor, ULG5,Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR)
    Cellular localisation: Cytoplasmic and Cell Surface
    分子量
    78-85kDa
    基因ID
    3973, 468490
    UniProt
    P22888
    途径
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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