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Recombinant LGALS1/Galectin 1 抗体 (AA 12-108)

This anti-LGALS1/Galectin 1 antibody is a 兔 单克隆 antibody detecting LGALS1/Galectin 1 in WB, ELISA, Coat 和 IHC (f). Suitable for 人.
产品编号 ABIN6937775
发货至: 中国

Quick Overview for Recombinant LGALS1/Galectin 1 抗体 (AA 12-108) (ABIN6937775)

抗原

See all LGALS1/Galectin 1 (LGALS1) 抗体
LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This LGALS1/Galectin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

GAL1-2499R
  • 抗原表位

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    AA 12-108

    特异性

    Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment (around aa 12-108) of human Galectin-1 protein (exact sequence is proprietary)

    亚型

    IgG
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL), ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: JEG-3, HeLa, K562 or 293 cells. Prostate, Kidney, Placenta, Stomach, Skin, Spleen, Brain or Heart.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

    别名

    LGALS1

    背景

    14 kDa laminin-binding protein, Beta-galactoside-binding lectin L-14-I, Gal-1, GAL1, Galaptin, Galectin-1, HLBP14, HPL, Lactose-binding lectin 1, Lect14, Lectin galactoside-binding soluble 1, LGALS1, MAPK activating protein MP12, S-Lac lectin 1,Galectin-1 / Human Placental Lactogen (hPL)
    Cellular localisation: Secreted (extracellular matrix)

    分子量

    14kDa

    基因ID

    3956, 445351

    UniProt

    P09382

    途径

    Carbohydrate Homeostasis
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