Recombinant LGALS1/Galectin 1 抗体 (AA 12-108)
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Quick Overview for Recombinant LGALS1/Galectin 1 抗体 (AA 12-108) (ABIN6937775)
抗原
See all LGALS1/Galectin 1 (LGALS1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 12-108
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特异性
- Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa 12-108) of human Galectin-1 protein (exact sequence is proprietary)
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亚型
- IgG
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anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) antibody
LGALS1 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1E8-1B2 unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) antibodyLGALS1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) antibodyLGALS1 适用: Cow WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 12-108) antibodyLGALS1 适用: 人 WB, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal GAL1-1831 unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) antibodyLGALS1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1H11C5 unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) antibodyKD Validated LGALS1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6025 unconjugated Recombinant Antibody
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 12-108) antibodyLGALS1 适用: 人 IHC, ELISA, Coat, StM 宿主: 兔 Monoclonal GAL1-2499R unconjugated Recombinant Antibody
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) antibodyKO Validated LGALS1 适用: 人 WB, IP, ICC, IF, IHC (p), IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) antibodyLGALS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) antibodyKD Validated LGALS1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6280 unconjugated Recombinant Antibody
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: JEG-3, HeLa, K562 or 293 cells. Prostate, Kidney, Placenta, Stomach, Skin, Spleen, Brain or Heart.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
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别名
- LGALS1
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背景
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14 kDa laminin-binding protein, Beta-galactoside-binding lectin L-14-I, Gal-1, GAL1, Galaptin, Galectin-1, HLBP14, HPL, Lactose-binding lectin 1, Lect14, Lectin galactoside-binding soluble 1, LGALS1, MAPK activating protein MP12, S-Lac lectin 1,Galectin-1 / Human Placental Lactogen (hPL)
Cellular localisation: Secreted (extracellular matrix) -
分子量
- 14kDa
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基因ID
- 3956, 445351
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UniProt
- P09382
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途径
- Carbohydrate Homeostasis
抗原
-
