IL7R 抗体 (AA 21-236)
Quick Overview for IL7R 抗体 (AA 21-236) (ABIN6937563)
抗原
See all IL7R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 21-236
-
特异性
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).
-
交叉反应 (详细)
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant fragment (around aa 21-236) of human CD127 protein (IL7R) (exact sequence is proprietary)
-
亚型
- IgG2c kappa
-
-
-
-
应用备注
-
Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: K562, HeLa, Daudi or Jurkat cells. Tonsil, Lymph Node or Spleen.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- IL7R (Interleukin 7 Receptor (IL7R))
-
别名
- IL7R
-
背景
-
CD127, IL-7 receptor subunit alpha, IL-7R-alpha, IL7R, IL7RA, IL7R alpha, ILRA, Interleukin 7 receptor alpha chain, Interleukin 7 receptor,CD127 / IL7R (Marker of T-Reg Cells)
Cellular localisation: Cell Surface and Cytoplasmic -
分子量
- 52-72kDa
-
基因ID
- 3575, 591742, 635723
-
UniProt
- P16871
-
途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
抗原
-