IgD 抗体
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- 抗原 See all IgD 抗体
- IgD
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IgD antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Full-length human IGHD protein
- 克隆位点
- IgD26
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product IgD Primary Antibody
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anti-IgD antibody
适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-IgD (AA 1-240) antibody适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IgD antibody适用: 人 IHC 宿主: 兔 Monoclonal MSVA-701R unconjugated Recombinant Antibody
anti-IgD antibody适用: 人 FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal IgD26 unconjugated
anti-IgD (AA 1-576) antibody适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-IgD (AA 111-160) antibody适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IgD antibody (FITC)GMP Grade 适用: 人 宿主: 小鼠 Monoclonal IA6-2 FITC
anti-IgD antibody (iFluor™647)GMP Grade 适用: 人 宿主: 小鼠 Monoclonal IA6-2 iFluor™647
anti-IgD antibody (iFluor™700)GMP Grade 适用: 人 宿主: 小鼠 Monoclonal IA6-2 iFluor™700
anti-IgD antibody (mFluor™450)GMP Grade 适用: 人 宿主: 小鼠 Monoclonal IA6-2 mFluor™450
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1 mM EDTA buffer, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Human tonsil lysate, NAMALWA cell lysate, Human tonsil and lymphoid tissues.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- IgD
- 别名
- IGHD (IgD 产品)
- 别名
- IgD antibody, Igh-5 antibody, immunoglobulin heavy constant delta antibody, immunoglobulin delta heavy chain constant region antibody, Ighd antibody, Igd antibody, IGHD antibody
- 物质类
- Antibody
- 背景
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Ig delta chain C region, IGHD, Immunoglobulin heavy constant delta,IgD (Immunoglobulin Delta Heavy Chain) (B-Cell Marker)
Cellular localisation: Cytoplasmic - 分子量
- 44-80kDa (heavy chain), 21-25kDa (kappa light chain)
- 基因ID
- 3495, 510635
- UniProt
- P01880
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