HLA-DRA 抗体
Quick Overview for HLA-DRA 抗体 (ABIN6937414)
抗原
See all HLA-DRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This MAb reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Raji cells
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亚型
- IgG2a kappa
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anti-HLA Class II DR alpha (HLA-DRA) (AA 26-254) antibody
HLA-DRA 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 1C11A5 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 26-216) antibodyHLA-DRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 27-216) antibodyHLA-DRA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 1-254) antibodyHLA-DRA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal 19-26-1-same as MB-26-1 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-470R unconjugated Recombinant Antibody
anti-HLA Class II DR alpha (HLA-DRA) (AA 26-221) antibody (APC)HLA-DRA 适用: 兔 WB, IHC 宿主: 豚鼠 Polyclonal APC
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人, Cow, Cat FACS, IF 宿主: 小鼠 Monoclonal 169-1B5-2 unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Raji, Ramos, Daudi or HuT78 cells. Tonsil or lymph node.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- HLA-DRA (HLA Class II DR alpha (HLA-DRA))
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别名
- HLA-DRA
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背景
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DR alpha chain, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen DR alpha chain, HLA DRA, HLA DRA1, HLA-DRA, HLADRA1, Major histocompatibility complex class II DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA,HLA-DRA (MHC II)
Cellular localisation: Cell surface -
分子量
- 36kDa (α, chain) and 27kDa (β, chain)
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基因ID
- 3122, 520048
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UniProt
- P01903
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途径
- TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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