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Recombinant FTL 抗体 (AA 38-165)

This anti-FTL antibody is a 小鼠 单克隆 antibody detecting FTL in WB 和 IHC (f). Suitable for 人.
产品编号 ABIN6937277
发货至: 中国

Quick Overview for Recombinant FTL 抗体 (AA 38-165) (ABIN6937277)

抗原

See all FTL 抗体
FTL (Ferritin, Light Polypeptide (FTL))

抗体类型

Recombinant Antibody

适用

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宿主

  • 88
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小鼠

克隆类型

  • 105
  • 72
单克隆

标记

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This FTL antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

RFTL-1388
  • 抗原表位

    • 73
    • 16
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    AA 38-165

    特异性

    Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Kidney, Cerebellum or Testis.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    FTL (Ferritin, Light Polypeptide (FTL))

    别名

    FTL

    背景

    Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3,Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker)
    Cellular localisation: Cytoplasmic

    分子量

    19-25kDa

    基因ID

    2512, 433670

    UniProt

    P02792

    途径

    Transition Metal Ion Homeostasis
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