FTL 抗体 (AA 38-165)
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- 抗原 See all FTL 抗体
- FTL (Ferritin, Light Polypeptide (FTL))
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抗原表位
- AA 38-165
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FTL antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)
- 特异性
- Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)
- 克隆位点
- FTL-1386
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product FTL Primary Antibody
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- 应用备注
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Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Immunohistology (Formalin-fixed) (0.25-0.5 μg/mL for 30 min at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
Positive_Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Kidney, Cerebellum or Testis.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- FTL (Ferritin, Light Polypeptide (FTL))
- 别名
- FTL (FTL 产品)
- 别名
- NBIA3 antibody, apoferritin antibody, ferritin antibody, fhc antibody, fth antibody, fth1 antibody, fthl6 antibody, ftn-2 antibody, pig15 antibody, plif antibody, FT antibody, Ftl antibody, Ftl-1 antibody, L-ferritin antibody, FTL antibody, Ftl1 antibody, FTL2 antibody, FTD antibody, ferritin light chain antibody, ferritin, heavy polypeptide 1 L homeolog antibody, ferritin light polypeptide 1 antibody, ferritin, light polypeptide antibody, ferritin light-chain antibody, ferritin light chain 1 antibody, FTL antibody, fth1.L antibody, Ftl1 antibody, CpipJ_CPIJ004069 antibody, Ftl antibody
- 背景
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Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3,Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker)
Cellular localisation: Cytoplasmic - 分子量
- 19-25kDa
- 基因ID
- 2512, 433670
- UniProt
- P02792
- 途径
- Transition Metal Ion Homeostasis
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