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FLT3 抗体

FLT3 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal FLT3-2458 unconjugated
产品编号 ABIN6937238
发货至: 中国
  • 抗原 See all FLT3 抗体
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    适用
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    宿主
    • 157
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    小鼠
    克隆类型
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    单克隆
    标记
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    This FLT3 antibody is un-conjugated
    应用范围
    • 126
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85 % identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human FLT3 protein
    克隆位点
    FLT3-2458
    亚型
    IgG2b kappa
    Top Product
    Discover our top product FLT3 Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Human lymph node or MDAMB468 xenograft.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    别名
    FLT3 (FLT3 产品)
    别名
    FLT3 antibody, B230315G04 antibody, CD135 antibody, Flk-2 antibody, Flk2 antibody, Flt-3 antibody, Ly72 antibody, wmfl antibody, FLK-2 antibody, FLK2 antibody, STK1 antibody, fms related tyrosine kinase 3 antibody, FMS-like tyrosine kinase 3 antibody, fms-related tyrosine kinase 3 antibody, FLT3 antibody, Flt3 antibody
    背景
    CD135, CD135 antigen, Fetal liver kinase 2, FL cytokine receptor, Flk2, FLT-3, Flt3, FLT3_HUMAN, FMS like tyrosine kinase 3, Fms related tyrosine kinase 3, Growth factor receptor tyrosine kinase type III, Ly-72, OTTHUMP0000004234, Receptor type tyrosine protein kinase FLT3, Stem cell tyrosine kinase 1, Stk 1, STK-1, Stk1, Tyrosine protein kinase receptor FLT3,Flt3 / CD135
    Cellular localisation: Membrane
    分子量
    160kDa
    基因ID
    2322, 507590
    UniProt
    P36888
    途径
    RTK signaling
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