FLT3 抗体
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- 抗原 See all FLT3 抗体
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FLT3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85 % identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human FLT3 protein
- 克隆位点
- FLT3-2458
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product FLT3 Primary Antibody
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human lymph node or MDAMB468 xenograft.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
- 别名
- FLT3 (FLT3 产品)
- 别名
- FLT3 antibody, B230315G04 antibody, CD135 antibody, Flk-2 antibody, Flk2 antibody, Flt-3 antibody, Ly72 antibody, wmfl antibody, FLK-2 antibody, FLK2 antibody, STK1 antibody, fms related tyrosine kinase 3 antibody, FMS-like tyrosine kinase 3 antibody, fms-related tyrosine kinase 3 antibody, FLT3 antibody, Flt3 antibody
- 背景
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CD135, CD135 antigen, Fetal liver kinase 2, FL cytokine receptor, Flk2, FLT-3, Flt3, FLT3_HUMAN, FMS like tyrosine kinase 3, Fms related tyrosine kinase 3, Growth factor receptor tyrosine kinase type III, Ly-72, OTTHUMP0000004234, Receptor type tyrosine protein kinase FLT3, Stem cell tyrosine kinase 1, Stk 1, STK-1, Stk1, Tyrosine protein kinase receptor FLT3,Flt3 / CD135
Cellular localisation: Membrane - 分子量
- 160kDa
- 基因ID
- 2322, 507590
- UniProt
- P36888
- 途径
- RTK signaling
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