FABP5 抗体
Quick Overview for FABP5 抗体 (ABIN6937209)
抗原
See all FABP5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.
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交叉反应 (详细)
- Human. Others-not tested.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human FABP5 protein
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亚型
- IgG2a kappa
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应用备注
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Known_Application: Western Blotting (1-2 μg/mL), ,Immunohistology (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, MOLT-4 and HEK-293 cell lines. Esophagus, Skin. Keratinocytes, highly expressed in psoriatic skin. Colon.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))
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别名
- FABP5
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背景
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FABP5, E-FABP, EFABP, PA-FABP, PAFABP,FABP5 (Marker of Metastatic Potential in Colorectal Cancer)
Cellular localisation: Nuclear and Cytoplasmic -
分子量
- 15.4kDa
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基因ID
- 2171, 408061
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UniProt
- Q01469
抗原
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