ETS1 抗体 (AA 137-230)
Quick Overview for ETS1 抗体 (AA 137-230) (ABIN6937200)
抗原
See all ETS1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 137-230
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特异性
- ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human ETS1 fragment (around aa137-230) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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应用备注
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: HepG2 and HeLa cells. Tonsil, Skin, Pancreas, Kidney and Lymphoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))
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别名
- ETS1
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背景
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Avian erythroblastosis virus E26 (v ets) oncogene homolog 1, ETS1, EWSR2, p54, v-ets erythroblastosis virus E26 oncogene homolog 1,ETS1 (Marker of Tumor Metastasis)
Cellular localisation: Nuclear -
分子量
- 54kDa
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基因ID
- 2113, 369438
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UniProt
- P14921
抗原
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