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ErbB2/Her2 抗体 (Intracellular)

This 小鼠 单克隆 antibody specifically detects ErbB2/Her2 in IF, ELISA, FACS 和 Coat. It exhibits reactivity toward 人.
产品编号 ABIN6937178
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ErbB2/Her2 抗体 (Intracellular) (ABIN6937178)

抗原

See all ErbB2/Her2 抗体
ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

适用

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小鼠

克隆类型

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单克隆

标记

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This ErbB2/Her2 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), ELISA, Flow Cytometry (FACS), Coating (Coat)

克隆位点

ERB2-776
  • 抗原表位

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    Intracellular

    特异性

    This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant intracellular domain of human HER-2 protein

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7, SKBR-3 cells. Breast Cancers.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

    别名

    ERBB2

    背景

    P185, CD340, Verb b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog,HER-2 / c-erbB-2 / neu / CD340
    Cellular localisation: Cell Surface

    分子量

    185kDa

    基因ID

    2064, 446352

    UniProt

    P04626

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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