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DNMT1 抗体 (AA 767-912)

DNMT1 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal DNMT1-2061 unconjugated
产品编号 ABIN6937096
发货至: 中国
  • 抗原 See all DNMT1 抗体
    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
    抗原表位
    • 22
    • 16
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    • 12
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    • 1
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    AA 767-912
    适用
    • 185
    • 55
    • 46
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 148
    • 36
    • 1
    • 1
    小鼠
    克隆类型
    • 138
    • 48
    单克隆
    标记
    • 76
    • 15
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    This DNMT1 antibody is un-conjugated
    应用范围
    • 115
    • 63
    • 45
    • 38
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    • 20
    • 15
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    • 6
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant human DNMT1 protein fragment (around aa 767-912) (exact sequence is proprietary)
    克隆位点
    DNMT1-2061
    亚型
    IgG2b kappa
    Top Product
    Discover our top product DNMT1 Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Raji cells. Tonsil or Placenta.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
    别名
    DNMT1 (DNMT1 产品)
    别名
    cb1075 antibody, cb983 antibody, dmnt1 antibody, fb05h01 antibody, mta antibody, wu:fb05h01 antibody, ADCADN antibody, AIM antibody, CXXC9 antibody, DNMT antibody, HSN1E antibody, MCMT antibody, DDM2 antibody, DECREASED DNA METHYLATION 2 antibody, DMT01 antibody, DMT1 antibody, DNA METHYLTRANSFERASE antibody, DNA METHYLTRANSFERASE 01 antibody, DNA METHYLTRANSFERASE 1 antibody, MET2 antibody, METHYLTRANSFERASE 2 antibody, METHYLTRANSFERASE I antibody, METI antibody, methyltransferase 1 antibody, Cxxc9 antibody, Dnmt antibody, Dnmt1o antibody, MTase antibody, Met-1 antibody, Met1 antibody, MommeD2 antibody, m.MmuI antibody, DNA methyltransferase 1 antibody, DNA (cytosine-5-)-methyltransferase 1 antibody, methyltransferase 1 antibody, DNA methyltransferase (cytosine-5) 1 antibody, DNMT1 antibody, dnmt1 antibody, Dnmt1 antibody, MET1 antibody
    背景
    ADCADN, AIM, CXXC-type zinc finger protein 9, CXXC9, DNA methyltransferase 1 (DNMT1), HSN1E, MCMT, Met1, MommeD2,DNMT1 / DNA Methyltransferase 1
    Cellular localisation: Nuclear
    分子量
    184kDa
    基因ID
    1786, 202672
    UniProt
    P26358
    途径
    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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