CDX2 抗体
Quick Overview for CDX2 抗体 (ABIN6936923)
抗原
See all CDX2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length CDX2 protein
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亚型
- IgG1 kappa
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anti-Caudal Type Homeobox 2 (CDX2) antibody
CDX2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Caudal Type Homeobox 2 (CDX2) (AA 1-180) antibodyCDX2 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5B4C1 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) (AA 1-313) antibodyCDX2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) (AA 176-303) antibodyCDX2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G9B9 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) (AA 150-249) antibodyCDX2 适用: 人 ELISA, Coat, IHC (f), ISt 宿主: 小鼠 Monoclonal CDX2-1690 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) antibodyCDX2 适用: 人, Synthetic IHC (f) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Caudal Type Homeobox 2 (CDX2) (AA 1-30) antibodyCDX2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caudal Type Homeobox 2 (CDX2) antibodyCDX2 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) antibodyCDX2 适用: 人, 小鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Caudal Type Homeobox 2 (CDX2) antibodyCDX2 适用: 人 IHC (f), ISt 宿主: 小鼠 Monoclonal CDX2-2214 unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: HT29 cells. Colon Carcinoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CDX2 (Caudal Type Homeobox 2 (CDX2))
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别名
- CDX2
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背景
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Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2,CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker)
Cellular localisation: Nuclear -
分子量
- 40kDa
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基因ID
- 1045, 174249
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UniProt
- Q99626
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途径
- Peptide Hormone Metabolism, Stem Cell Maintenance
抗原
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