CD81 抗体
Quick Overview for CD81 抗体 (ABIN6936836)
抗原
See all CD81 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
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交叉反应 （详细）
- Human. Mouse. Rat.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human CD81 protein
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亚型
- IgG1 kappa
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anti-CD81 (CD81) antibody
KO Validated CD81 适用: 人 FACS, WB, IF, IHC (p), ICC, BP 宿主: 兔 Polyclonal unconjugated
anti-CD81 (CD81) (AA 1-100) antibodyCD81 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD81 (CD81) antibodyCD81 适用: 人 FACS, WB, IHC, ELISA 宿主: 兔 Monoclonal 9F7 unconjugated Recombinant Antibody
anti-CD81 (CD81) antibodyCD81 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, IF, Func, StM 宿主: 小鼠 Monoclonal 1-3-3-22 unconjugated
anti-CD81 (CD81) antibodyCD81 适用: 人, 小鼠, 大鼠 ELISA, Coat 宿主: 兔 Monoclonal C81-2885R unconjugated Recombinant Antibody
anti-CD81 (CD81) antibodyCD81 适用: 人, 兔, Cat FACS, WB, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal M38 unconjugated
anti-CD81 (CD81) antibody (FITC)CD81 适用: 人, 兔, Cat FACS 宿主: 小鼠 Monoclonal M38 FITC
anti-CD81 (CD81) antibody (PE)CD81 适用: 人, 兔, Cat FACS 宿主: 小鼠 Monoclonal M38 PE
anti-CD81 (CD81) antibodyCD81 适用: 人 FACS, cELISA 宿主: 大鼠 Monoclonal QV-6A8-S3 unconjugated
anti-CD81 (CD81) antibodyCD81 适用: 人, 兔, Cat FACS, WB, IP, Func, IHC (p), ICC 宿主: 小鼠 Monoclonal M38 unconjugated
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应用备注
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Known_Application: Functional Studies (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL for 2 hours at RT),Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7, Ramos, Daudi or Jurkat cells. Human lymphocytes. Human tonsil or liver.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD81
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别名
- CD81
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背景
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CD81, Target of the antiproliferative antibody 1 (TAPA-1), Tetraspanin-28, Tspan-28,CD81 / TAPA-1
Cellular localisation: Cell surface -
分子量
- 26kDa
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基因ID
- 975, 54457
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UniProt
- P60033
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途径
- Inositol Metabolic Process, Hepatitis C
抗原
-
