CD7 抗体
Quick Overview for CD7 抗体 (ABIN6936798)
抗原
See all CD7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length CD7 protein
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亚型
- IgG1 kappa
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anti-CD7 (CD7) (AA 26-134) antibody
CD7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 23-128) antibodyCD7 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 3D11F12 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 FACS, WB, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-186 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2B1C9 unconjugated
anti-CD7 (CD7) (AA 72-175) antibodyCD7 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 5B10E3 unconjugated
anti-CD7 (CD7) (AA 24-150) antibodyCD7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 21-240) antibodyCD7 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-007R unconjugated Recombinant Antibody
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应用备注
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Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat, HUT-78, Molt-4, CEM cells or human peripheral blood lymphocytes. Lymph node and tonsil.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD7
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别名
- CD7
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背景
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GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41,CD7 (T-Cell Leukemia Marker)
Cellular localisation: Cell Surface -
分子量
- 40kDa
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基因ID
- 924, 186820
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UniProt
- P09564
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途径
- Cell-Cell Junction Organization
抗原
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