CD6 抗体
Quick Overview for CD6 抗体 (ABIN6936765)
抗原
See all CD6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Human rheumatoid synovial T cell line ST-1
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亚型
- IgG1 kappa
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anti-CD6 (CD6) (AA 18-199) antibody
CD6 适用: 人 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5A10A2 unconjugated
anti-CD6 (CD6) (AA 18-199) antibodyCD6 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6B11G6 unconjugated
anti-CD6 (CD6) (AA 472-668) antibodyCD6 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 6B9 unconjugated
anti-CD6 (CD6) (AA 30-204) antibodyCD6 适用: 小鼠 FACS, WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD6 (CD6) (AA 477-644) antibodyCD6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD6 (CD6) antibodyCD6 适用: 人 FACS, IF, IHC, StM 宿主: 兔 Monoclonal C6-2884R unconjugated Recombinant Antibody
anti-CD6 (CD6) antibodyCD6 适用: 人 FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal 3F7B5 unconjugated
anti-CD6 (CD6) (AA 472-668) antibodyCD6 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-CD6 (CD6) (AA 424-668) antibodyCD6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD6 (CD6) antibodyCD6 适用: 人, 小鼠 FACS, IF 宿主: 小鼠 Monoclonal SPV-L14 unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MOLT-4, CCRF-CEM, Jurkat cells, Tonsil.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD6
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别名
- CD6
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背景
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T12, TP120,CD6 (Negative Marker of T-regulatory Cells)
Cellular localisation: Cell surface and cytoplasmic -
分子量
- 90-130kDa
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基因ID
- 923, 744366
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UniProt
- P30203
抗原
-
