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CD55 抗体

CD55 适用: 人 FACS, IF, DNA Mic, DNA Mic 宿主: 小鼠 Monoclonal F4-29D9 unconjugated
产品编号 ABIN6936757
发货至: 中国
  • 抗原 See all CD55 抗体
    CD55 (Complement Decay-Accelerating Factor (CD55))
    适用
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    宿主
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    小鼠
    克隆类型
    • 80
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    单克隆
    标记
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    This CD55 antibody is un-conjugated
    应用范围
    • 98
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    Flow Cytometry (FACS), Immunofluorescence (IF), DNA Microscopy (DNA Mic), DNA Microscopy (DNA Mic)
    特异性
    Recognizes a single chain glycoprotein of 70 kDa, identified as CD55. This MAb was clustered in Kobe at the Sixth International Workshop on Human Leukocyte Differentiation Antigens as F429D-9 (N-L120). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. Anti-CD55 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Human umbilical vein endothelial cells (HUVEC)
    克隆位点
    F4-29D9
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD55 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: Jurkat, HUT-78, K562, YT, U937, MG63 and human lymphocytes. Human lymph nodes and tonsils.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CD55 (Complement Decay-Accelerating Factor (CD55))
    别名
    CD55 (CD55 产品)
    别名
    CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody
    背景
    CD55, CD55 Cromer blood group system, Complement decay-accelerating factor, CROM, DAF, Decay Accelerating Factor for Complement, Decay accelerating factor GPI-form, Decay accelerating factor soluble-form, GPI-DAF,CD55 / Decay Accelerating Factor (DAF)
    Cellular localisation: Cell Surface
    分子量
    70kDa
    基因ID
    1604, 126517
    UniProt
    P08174
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity
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