CD5 抗体 (AA 269-366)
Quick Overview for CD5 抗体 (AA 269-366) (ABIN6936751)
抗原
See all CD5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 269-366
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特异性
- Recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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anti-CD5 (CD5) (AA 105-210) antibody
CD5 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
anti-CD5 (CD5) (AA 269-366) antibodyCD5 适用: 人 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal CD5-2416 unconjugated
anti-CD5 (CD5) (AA 25-372) antibodyCD5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD5 (CD5) (AA 269-366) antibodyCD5 适用: 人 FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal CD5-2418 unconjugated
anti-CD5 (CD5) antibodyCD5 适用: 人 FACS, WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal L17F12 unconjugated
anti-CD5 (CD5) (AA 403-495) antibodyCD5 适用: 人, 小鼠 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 6C3B2 unconjugated
anti-CD5 (CD5) (AA 27-233) antibodyCD5 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 6A11 unconjugated
anti-CD5 (CD5) (AA 403-495) antibodyCD5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-CD5 (CD5) antibodyCD5 适用: 人 FACS, WB, IP, ELISA, IHC (p) 宿主: 小鼠 Monoclonal MEM-32 unconjugated
anti-CD5 (CD5) antibodyCD5 适用: 人 FACS, WB, IP, ELISA, IHC (fro) 宿主: 小鼠 Monoclonal CRIS1 unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Immunofluorescence (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: 293T, Ramos or MOLT-4 cells. Tonsil or Lymph Node.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD5
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别名
- CD5
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背景
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CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, T-cell surface glycoprotein CD5,CD5 (Mantle Cell Lymphoma Marker)
Cellular localisation: Cell Surface -
分子量
- 67kDa
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基因ID
- 921, 58685
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UniProt
- P06127
抗原
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