CD5 抗体
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北京 101111
Quick Overview for CD5 抗体 (ABIN6936749)
抗原
See all CD5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD5 (Mantle Cell Lymphoma Marker) Antibody
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特异性
- Recognizes a 67 kDa transmembrane protein, which is identified as CD5 (HLDA I, WS Code T 29HLDA III, WS Code T 530). The CD5 antigen is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms.
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交叉反应 (详细)
- Human. Rhesus Monkey.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Stimulated human leukocytes
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亚型
- IgG2a, kappa
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Functional Studies (Order Ab without BSA & Azide), Immunoprecipitation (0.5-1 μg/500 μg protein lysate), Optimal dilution for a specific application should be determined.
Positive_Control: 293T, Ramos or MOLT-4 cells. Tonsil.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CD5
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别名
- CD5
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背景
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CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, T-cell surface glycoprotein CD5
293T, Ramos or MOLT-4 cells. Tonsil.
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分子量
- ~67kDa
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基因ID
- 921, 58685
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UniProt
- P06127
抗原
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