CD5 抗体
Our Local Distributor
北京 101111
Quick Overview for CD5 抗体 (ABIN6936748)
抗原
See all CD5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- CD5 (Mantle Cell Lymphoma Marker) Antibody
-
特异性
- Recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
-
交叉反应 （详细）
- Human. Rabbit. Cow. Rat.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Human CD5 recombinant protein (C5/473), A synthetic peptide from the intracellular region of human CD5 (CD5/54/F6)
-
亚型
- IgG1, kappa
-
-
anti-CD5 (CD5) (AA 269-366) antibody
CD5 适用: 人 FACS, WB, IHC, IF 宿主: 小鼠 Monoclonal CD5-2416 unconjugated
anti-CD5 (CD5) (AA 105-210) antibodyCD5 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-CD5 (CD5) (AA 25-372) antibodyCD5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD5 (CD5) (AA 269-366) antibodyCD5 适用: 人 FACS, IHC, IF 宿主: 小鼠 Monoclonal CD5-2418 unconjugated
anti-CD5 (CD5) (AA 27-233) antibodyCD5 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 6A11 unconjugated
anti-CD5 (CD5) (AA 403-495) antibodyCD5 适用: 人, 小鼠 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 6C3B2 unconjugated
anti-CD5 (CD5) antibodyCD5 适用: 人 FACS, WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal L17F12 unconjugated
anti-CD5 (CD5) (AA 403-495) antibodyCD5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-CD5 (CD5) (AA 25-371) antibodyCD5 适用: 人 WB, IHC, ICC 宿主: 兔 Monoclonal BLR218K unconjugated Recombinant Antibody
anti-CD5 (CD5) (AA 25-372) antibodyCD5 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 3D3G6 unconjugated
-
-
应用备注
-
Known_Application: ELISA (For coating use Ab at 1-2 μg/mL order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1 mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: 293T, Ramos or MOLT-4 cells. Tonsil.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- CD5
-
别名
- CD5
-
背景
-
CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, T-cell surface glycoprotein CD5
293T, Ramos or MOLT-4 cells. Tonsil.
-
分子量
- ~67kDa
-
基因ID
- 921, 58685
-
UniProt
- P06127
抗原
-
