CD37 抗体
Quick Overview for CD37 抗体 (ABIN6936679)
抗原
See all CD37 (TSPAN26) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes a protein of 33-55kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Spleen cells of a patient with hairy cell leukemia
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亚型
- IgG2b kappa
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anti-Tetraspanin 26 (TSPAN26) (AA 109-237) antibody
TSPAN26 适用: 人 ELISA, IF, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 26 (TSPAN26) antibodyTSPAN26 适用: 人 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal MB-1 unconjugated
anti-Tetraspanin 26 (TSPAN26) antibody (PE)TSPAN26 适用: 人 FACS 宿主: 小鼠 Monoclonal MB-1 PE
anti-Tetraspanin 26 (TSPAN26) antibodyTSPAN26 适用: 人 FACS, IF, Func 宿主: 小鼠 Monoclonal IPO-24 unconjugated
anti-Tetraspanin 26 (TSPAN26) antibodyTSPAN26 适用: 人, 小鼠 ELISA, ICC 宿主: 小鼠 Monoclonal 2B8 unconjugated
anti-Tetraspanin 26 (TSPAN26) antibody (PE)TSPAN26 适用: 人 FACS, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4AIPO-24 PE
anti-Tetraspanin 26 (TSPAN26) antibody (FITC)TSPAN26 适用: 人 FACS, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4AIPO-24 FITC
anti-Tetraspanin 26 (TSPAN26) (AA 112-241) antibodyTSPAN26 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM166 unconjugated
anti-Tetraspanin 26 (TSPAN26) (AA 126-175) antibodyTSPAN26 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 26 (TSPAN26) (AA 91-140) antibodyTSPAN26 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Functional Studies (Order Ab without Azide), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Daudi, Raji, Namalva, Ramos cells and human lymphocytes. Human tonsil and lymph node.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
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别名
- CD37
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背景
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Cell differentiation antigen 37, GP52 40, Tetraspanin-26, Tspan-26, TSPAN26,CD37 (Peripheral Mature B-Cell Marker)
Cellular localisation: Cell Surface -
分子量
- 33-55kDa
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基因ID
- 951, 166556
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UniProt
- P11049
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途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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