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CD34 抗体

CD34 适用: 人 FACS, IF, ELISA, Coat 宿主: 小鼠 Monoclonal ICO-115 unconjugated
产品编号 ABIN6936665
发货至: 中国
  • 抗原 See all CD34 抗体
    CD34
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD34 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Coating (Coat)
    特异性
    This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposi's sarcoma, but shows low specificity.
    交叉反应 (详细)
    Human. Rat.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Blast cells of a chronic myeloid leukemia patient
    克隆位点
    ICO-115
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD34 Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: KG-1 cells. Human tonsil or angiosarcoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CD34
    别名
    CD34 (CD34 产品)
    别名
    AU040960 antibody, CD34 molecule antibody, CD34 antigen antibody, CD34 antibody, Cd34 antibody
    背景
    Hematopoietic Progenitor Cell Antigen, HPCA1, Mucosialin,CD34 (Hematopoietic Stem Cell & Endothelial Marker)
    Cellular localisation: Cell surface
    分子量
    90-110kDa
    基因ID
    947, 374990
    UniProt
    P28906
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