CD1c 抗体
Quick Overview for CD1c 抗体 (ABIN6936628)
抗原
See all CD1c (CD1C) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with -2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1
-
交叉反应 （详细）
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant full-length human CD1c protein
-
亚型
- IgG1 kappa
-
-
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 18-302) antibody
CD1C 适用: 人 ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 3G1B3 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人 FACS, IHC, IP 宿主: 小鼠 Monoclonal L161 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1H9 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibody (APC)CD1C 适用: 人 FACS 宿主: 小鼠 Monoclonal L161 APC
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 18-300) antibodyCD1C 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人 ELISA, LMNX 宿主: 小鼠 Monoclonal OTI1F4 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 18-302) antibodyCD1C 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 小鼠 Monoclonal 1E10 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibody (PE)CD1C 适用: 人 FACS 宿主: 小鼠 Monoclonal L161 PE
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 226-253) antibodyCD1C 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Expressed on cortical thymocytes, on certain T-cell leukemias and in various other tissues.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
-
别名
- CD1C
-
背景
-
BDCA1, CD1, CD1A, CD1c, CD1C antigen c polypeptide, CD1c molecule, Cortical thymocyte antigen CD1C, Differentiation antigen CD1 alpha 3, R7, T cell surface glycoprotein CD1c,CD1c
Cellular localisation: Cell Surface -
分子量
- 43kDa
-
基因ID
- 911, 132448
-
UniProt
- P29017
抗原
-
