CD1b 抗体
Quick Overview for CD1b 抗体 (ABIN6936627)
抗原
See all CD1b (CD1B) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            特异性
- The Mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
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                                            交叉反应 (详细)
- Human.
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                                            纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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                                            免疫原
- Human peripheral lymphocytes
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                                            亚型
- IgG1 kappa
 
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                                            应用备注
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                        Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined. Positive_Control: MOLT4 cells. Human thymus. 
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                                            限制
- 仅限研究用
 
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                                            浓度
- 1.0 mg/mL
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                                            缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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                                            储存液
- Azide free
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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                                            有效期
- 24 months
 
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    - CD1b (CD1B)
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                                            别名
- CD1B
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                                            背景
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                        A1 domain, CD1B, Cortical thymocyte antigen CD1B, hTa1 thymocyte antigen, Ly38, T cell surface glycoprotein CD1b, T6/Leu6,CD1b (T-Cell Surface Glycoprotein)
 Cellular localisation: Cell surface
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                                            分子量
- 49kDa
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                                            基因ID
- 910, 1310
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                                            UniProt
- P29016
 抗原
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