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Cyclin A1 抗体

CCNA1 适用: 非洲爪蟾 WB 宿主: 小鼠 Monoclonal XLA1-3 unconjugated
产品编号 ABIN6936580
发货至: 中国
  • 抗原 See all Cyclin A1 (CCNA1) 抗体
    Cyclin A1 (CCNA1)
    适用
    • 36
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    非洲爪蟾
    宿主
    • 53
    • 7
    小鼠
    克隆类型
    • 55
    • 5
    单克隆
    标记
    • 29
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    This Cyclin A1 antibody is un-conjugated
    应用范围
    • 47
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    • 5
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    Western Blotting (WB)
    特异性
    The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F, and retinoblastoma protein p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34. The antibody detects Xenopus cyclin A in blots. Cyclin A1 is the embryonic cyclin which is present in Xenopus eggs. This MAb only detects Xenopus Cyclin A1.
    交叉反应 (详细)
    Xenopus laevis
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length Xenopus laevis Cyclin A1 protein
    克隆位点
    XLA1-3
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CCNA1 Primary Antibody
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: Very high levels in testis. Also found in myeloid leukemia cell lines. Xenopus laevis tissue lysate.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Cyclin A1 (CCNA1)
    别名
    ccna1 (CCNA1 产品)
    别名
    fd14f08 antibody, wu:fd14f08 antibody, wu:fi20d12 antibody, zgc:111869 antibody, MGC81965 antibody, cyclin-A1 antibody, CCNA1 antibody, MGC132235 antibody, cyclin-A1-2 antibody, Cyclin-A1 antibody, ccna1 antibody, cyclin A1 antibody, cyclin A1 L homeolog antibody, CYCLIN A1;2 antibody, cyclin A1 S homeolog antibody, CCNA1 antibody, ccna1 antibody, ccna1.L antibody, CYCA1;2 antibody, Ccna1 antibody, ccna1.S antibody
    背景
    CCN1, CCNA, CCNA2, Cyclin A1,Cyclin A1
    Cellular localisation: Nucleus.
    分子量
    65kDa
    基因ID
    4267
    UniProt
    P18606
    途径
    Apoptosis, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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