Cyclin A1 抗体
Quick Overview for Cyclin A1 抗体 (ABIN6936580)
抗原
See all Cyclin A1 (CCNA1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F, and retinoblastoma protein p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34. The antibody detects Xenopus cyclin A in blots. Cyclin A1 is the embryonic cyclin which is present in Xenopus eggs. This MAb only detects Xenopus Cyclin A1.
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交叉反应 （详细）
- Xenopus laevis
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length Xenopus laevis Cyclin A1 protein
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亚型
- IgG1 kappa
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anti-Cyclin A1 (CCNA1) antibody
CCNA1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) antibodyCCNA1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) (AA 211-310) antibodyCCNA1 适用: 小鼠, 大鼠, 绵羊 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) (AA 1-464) antibodyCCNA1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4A11-5B5 unconjugated
anti-Cyclin A1 (CCNA1) (C-Term) antibodyCCNA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) (C-Term) antibodyCCNA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) antibodyCCNA1 适用: 非洲爪蟾 WB 宿主: 小鼠 Monoclonal XLA1-3 unconjugated
anti-Cyclin A1 (CCNA1) (AA 1-230) antibodyCCNA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) (C-Term) antibodyCCNA1 适用: 人, 小鼠, 大鼠, Cow, 兔, 小鸡, 犬, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A1 (CCNA1) (AA 183-430) antibodyCCNA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Very high levels in testis. Also found in myeloid leukemia cell lines. Xenopus laevis tissue lysate.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Cyclin A1 (CCNA1)
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别名
- ccna1
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背景
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CCN1, CCNA, CCNA2, Cyclin A1,Cyclin A1
Cellular localisation: Nucleus. -
分子量
- 65kDa
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基因ID
- 4267
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UniProt
- P18606
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途径
- Apoptosis, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
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