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Aurora Kinase B 抗体 (AA 89-251)

AURKB 适用: 人 WB 宿主: 小鼠 Monoclonal AURKB-1521 unconjugated
产品编号 ABIN6936440
发货至: 中国
  • 抗原 See all Aurora Kinase B (AURKB) 抗体
    Aurora Kinase B (AURKB)
    抗原表位
    • 18
    • 18
    • 15
    • 13
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 89-251
    适用
    • 119
    • 67
    • 34
    • 12
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 117
    • 21
    • 3
    • 1
    小鼠
    克隆类型
    • 105
    • 38
    单克隆
    标记
    • 77
    • 11
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Aurora Kinase B antibody is un-conjugated
    应用范围
    • 88
    • 63
    • 40
    • 32
    • 17
    • 14
    • 13
    • 13
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Recognizes a protein of 39 kDa, which is identified as Aurora B. The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment (around aa 89-251) of human Aurora B protein (exact sequence is proprietary)
    克隆位点
    AURKB-1521
    亚型
    IgG1 kappa
    Top Product
    Discover our top product AURKB Primary Antibody
  • 应用备注

    Known_Application: Western Blot (1-2ug/ml); Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa cells. Tonsil, Placenta, Hodgkin's Lymphoma or Colon Carcinoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Aurora Kinase B (AURKB)
    别名
    AURKB (AURKB 产品)
    别名
    AIK2 antibody, AIM-1 antibody, AIM1 antibody, ARK2 antibody, AurB antibody, IPL1 antibody, PPP1R48 antibody, STK12 antibody, STK5 antibody, aurkb-sv1 antibody, aurkb-sv2 antibody, AIRK2 antibody, AL022959 antibody, Aik2 antibody, Aim1 antibody, Ark2 antibody, STK-1 antibody, Stk12 antibody, Stk5 antibody, Aur B antibody, Aurora B antibody, Aurora-B antibody, CG6620 antibody, DmAIRK2 antibody, DmAurB antibody, DmAuroraB antibody, Dmel\\CG6620 antibody, IAL antibody, IAL1 antibody, Ial antibody, aurB antibody, aurora B antibody, ARK-2 antibody, XAIRK2 antibody, aik2 antibody, aim-1 antibody, aim1 antibody, airk2 antibody, ark2 antibody, ipl1 antibody, stk12 antibody, stk5 antibody, CHUNP6896 antibody, fa09g06 antibody, stka antibody, wu:fa09g06 antibody, aurkb antibody, AIRK2-B antibody, XAIRK2-B antibody, aurkb-a antibody, aurkb-b antibody, xAurora-B-B antibody, aurora kinase B antibody, aurora B antibody, aurora kinase B S homeolog antibody, AURKB antibody, Aurkb antibody, aurB antibody, aurkb antibody, aurkb.S antibody
    背景
    AIK2, AIM-1, ARK-2, AurB, AURKB, Aurora-1, Aurora and Ipl1 like midbody associated protein 1, Aurora kinase B, Aurora-B, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, IPL1, Protein phosphatase 1 regulatory subunit 48 (PPP1R48), Serine/threonine-protein kinase 12, Serine/threonine-protein kinase aurora-B, STK1, STK12, STK5,Aurora B (Proliferation Marker)
    Cellular localisation: Nuclear and Cytoplasmic
    分子量
    39kDa
    基因ID
    9212, 442658
    UniProt
    Q96GD4
    途径
    TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
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