PLAP 抗体
Quick Overview for PLAP 抗体 (ABIN6936397)
抗原
See all PLAP (ALPP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- PLAP is a tissue specific, trophoblast-derived, 70kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+ metallo glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific AP's in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous. Non-tissue specific AP is found in kidney, liver and bone. This MAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP as to AP from normal human testis. This MAb can be used both as coating as well as tracer antibody in the same ELISA to detect PLAP in serum of S, F, FS and I phenotypes.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human ALPP protein
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亚型
- IgG2a kappa
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anti-Placental Alkaline Phosphatase (ALPP) (AA 162-312) antibody
ALPP 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Placental Alkaline Phosphatase (ALPP) antibodyALPP 适用: 人 IHC, ISt 宿主: 小鼠 Monoclonal ALP-870 unconjugated
anti-Placental Alkaline Phosphatase (ALPP) (N-Term) antibodyALPP 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Placental Alkaline Phosphatase (ALPP) antibodyALPP 适用: 人 IHC, ISt 宿主: 小鼠 Monoclonal GM022 unconjugated
anti-Placental Alkaline Phosphatase (ALPP) antibodyALPP 适用: 人 IHC, ISt 宿主: 兔 Monoclonal ALPP-2899R unconjugated Recombinant Antibody
anti-Placental Alkaline Phosphatase (ALPP) antibodyALPP 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-350R unconjugated Recombinant Antibody
anti-Placental Alkaline Phosphatase (ALPP) antibodyALPP 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3E5 unconjugated
anti-Placental Alkaline Phosphatase (ALPP) (N-Term) antibodyALPP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Placental Alkaline Phosphatase (ALPP) (AA 20-143) antibodyALPP 适用: 人 WB, ELISA, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Placental Alkaline Phosphatase (ALPP) (AA 534-792) antibodyALPP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: HepG2 cells. Placenta or seminoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
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别名
- ALPP
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背景
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Alkaline phosphatase placental type, Alkaline phosphatase Regan Isozyme, ALP, Alp1, ALPP, Germ-cell alkaline phosphatase, nagao Isozyme, PALP, Placental alkaline phosphatase 1, placental heat-stable alkaline phosphatase, PLAP-1, PLAP1,Alkaline Phosphatase (Placental) / PLAP (Germ Cell Tumor Marker)
Cellular localisation: Cytoplasmic and cell surface -
分子量
- 70kDa
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基因ID
- 250, 284255
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UniProt
- P05187
抗原
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