ALPL 抗体
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北京 101111
Quick Overview for ALPL 抗体 (ABIN6936393)
抗原
See all ALPL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Alkaline Phosphatase (Tissue-Nonspecific) Antibody
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特异性
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects.
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交叉反应 (详细)
- Human. Cow.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human ALPL protein
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亚型
- IgG1, kappa
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Intestine.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
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别名
- ALPL
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背景
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Alkaline phosphatase, germ cell, Alkaline phosphatase, testicular and thymus, Alkaline phosphatase liver/bone/kidney, Alkaline phosphatase, tissue-nonspecific, ALPG, ALPL, Germ cell alkaline phosphatase, Testicular and thymus alkaline phosphatase, Tissue non-specific alkaline phosphatase, Tissue nonspecific ALP (TNAP or TNSALP)
Intestine.
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分子量
- 55kDa
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基因ID
- 249, 75431
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UniProt
- P05186
抗原
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