AKR1C2 抗体
Quick Overview for AKR1C2 抗体 (ABIN6936375)
抗原
See all AKR1C2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- DDH2 / AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.
-
交叉反应 (详细)
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant human full-length AKR1C2 protein
-
亚型
- IgG2a kappa
-
-
-
-
应用备注
-
Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, K-562, A431, HepG2, A549 cells. Human liver or stomach tissue.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
-
别名
- AKR1C2
-
背景
-
AKR1C2, 3-alpha-HSD3, AKR1C-pseudo protein, BABP, Dihydrodiol dehydrogenase 2, DD-2, MCDR2, HAKRD, DD, DDH2, HBAB, Pseudo-chlordecone reductase, SRXY8,Aldo-keto Reductase Family 1 Member C2 / DD2
Cellular localisation: Cytoplasm. -
分子量
- 37kDa
-
基因ID
- 1646, 567256
-
UniProt
- P52895
-
途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
-